In recent years, Ghana has witnessed a concerning trend in substance abuse (opioid abuse), particularly among its youth.
Among the most alarming substances is a potent opioid known colloquially as “Red” or “225.” This pill, often misused for its euphoric effects, has become a symbol of a larger crisis, threatening not only the physical health of young individuals but also their social and economic futures.
As the youth represent the backbone of Ghana’s future, it is crucial to address this issue with urgency, providing education and support to combat the rising tide of opioid addiction.
After years of battling mental illness, Ghanaian Hiplife musician Okomfour Kwadee has made a public return, appearing stable and composed in a recent interview.
Speaking in a conversation shared on social media, Kwadee cautioned Ghanaian youth against the use of opioids, particularly a highly addictive pill known as “Red” or “225”.
He stressed that the substance offers no benefit and could be fatal. The musician revealed that he had experimented with various stimulants in the past, which took a toll on his health.
“I will admonish the youth to engage in activities that would benefit them. Doctors have spoken against the intake of Red because if you take it, you can die from it. We have been in the system for some time now, and I have done everything. There is no strength greater than the one you have. The Red, tramadol, and other stimulants are of no benefit.”
Okomfour Kwadee
Kwadee also urged fellow musicians to refrain from using marijuana and other harmful substances, warning that blind imitation of foreign trends is damaging the creative industry.
“I know the drugs are plenty in the system, but the common one right now is 225 or Red. Foreign influence is also a factor, as most of these musicians are trying to copy them blindly. These days, the whole thing has become like a fashion; they should note that they can’t smoke forever because it’s not helpful.”
Okomfour Kwadee
Meanwhile, the veteran musician has launched a campaign to discourage the use of “Red”, calling for collective action to protect the health and future of Ghana’s youth.
“Red” and “225” are often misused for their psychoactive properties, leading to a state of euphoria that many young people seek as an escape from the pressures of life.
However, what begins as recreational use quickly spirals into addiction. Opioids, by their very nature, are highly addictive, and the transition from casual use to dependency occurs rapidly.
The World Health Organization has identified opioid addiction as a public health crisis, and Ghana is not immune to this trend. The ease of access to these substances, combined with a lack of awareness about their dangers, has created a perfect storm for addiction among the youth.
Consequences of Opioid Abuse

The ramifications of opioid abuse are dire and multifaceted. Physically, young individuals experience a range of health issues, including respiratory depression, overdose, and a host of other medical complications.
Psychologically, the impact is equally devastating, leading to mental health disorders, social isolation, and a decline in academic performance.
Economically, the cost of addiction burdens families and communities, diverting resources away from essential services and perpetuating cycles of poverty and instability.
Moreover, the social implications of opioid addiction are profound. As young people become increasingly dependent on substances like “Red” and “225,” their ability to contribute positively to society diminishes.
This not only affects their personal lives but also has a ripple effect on families, schools, and communities, leading to a broader societal crisis.
To combat this growing epidemic, a multifaceted approach is essential. Education is a powerful tool in preventing opioid abuse.
Schools and community organizations must prioritize awareness campaigns that inform young people about the dangers of opioid misuse. Workshops, seminars, and peer-led discussions equip young people with the knowledge they need to make informed decisions.

Additionally, families play a crucial role in prevention. Open dialogues about substance use, mental health, and coping mechanisms create a supportive environment for young individuals.
Parents should be encouraged to monitor their children’s behaviors and seek help if they notice signs of substance abuse.
The government also has a critical role in addressing the opioid crisis. Policymakers must implement stricter regulations on the availability of these substances and invest in public health campaigns that highlight the risks associated with opioid abuse.
The misuse of opioids, particularly the pills known as “Red” and “225,” represents a growing crisis among Ghanaian youth that demands immediate attention.
It is a collective responsibility—families, educators, healthcare providers, and government officials must unite to combat this epidemic.
By fostering awareness, promoting education, and providing essential support services, it protects the health and future of the youth.
It is time to take action against the opioid crisis and ensure that the next generation of Ghanaians thrives without the shadow of addiction looming over them.