More than a million people around the world have now died in the coronavirus pandemic with many regions still reporting surging numbers of new infections.
The data from Johns Hopkins University, which has been tracking the outbreak, also shows more than 33 million COVID-19 cases have been reported.
It comes after a significant rise in infections has triggered local lockdowns in countries such as France, Spain and the UK.
Coronavirus cases have been reported in more than 210 countries since the first cases were identified in Wuhan, China, in December 2019.
On 22 September, the death toll in the United States, which has suffered more fatalities than any other country, passed 200,000.
India has the fastest infection rate in the world and is close to becoming the country with the highest number of cases.
The nation of 1.3 billion people currently has around 5.9 million infections – second only to the US, which has recorded more than seven million.
However, India’s fatality rate is one of the lowest in the world, with experts saying it may be down to reasons such as its younger population.
Rio de Janeiro’s Carnival, meanwhile, has been postponed for the first time in a century as Brazil continues to battle the second-deadliest coronavirus outbreak in the world.
Israel, which in September became the first country to re-enter a strict national lockdown, has voted to further tighten measures after restrictions failed to bring down the infection rate.
In the UK, around 17 million people, more than a quarter of the population, are living under tougher coronavirus restrictions after new measures on socialising came into force in large parts of the country.
In Africa, the World Health Organisation has said the outbreak may have passed its peak, but warned governments against complacency to avoid a second wave.
UN Secretary-General António Guterres called it a “mind-numbing” figure and “an agonising milestone”.
“Yet we must never lose sight of each and every individual life.
“They were fathers and mothers, wives and husbands, brothers and sisters, friends and colleagues. The pain has been multiplied by the savageness of this disease,” he said in a video message.
The WHO’s emergencies chief has warned the number of global coronavirus deaths could reach two million without concerted action to curb the pandemic.
“It’s certainly unimaginable,” said Dr Mike Ryan.
“But it’s not impossible, because if we look at losing a million people in nine months and then we just look at the realities of getting a vaccine out there in the next nine months, it’s a big task for everyone involved.
“There’s the issue of funding these vaccines. There’s the issue of distributing these vaccines and then the issues of acceptance.
“And beyond that, with the work we still have to do in controlling this disease. And remember, we have things we can do now to drive transmission down and drive down the number of deaths.”
Many countries are experiencing a second wave of infections and with winter approaching, it is unknown what impact the cold months will have on the disease, and how it will interact with other seasonal respiratory viruses.